백서 좌골신경의 압좌상과 절제에 따른 말초신경 재생의 비교
Comparision of peripheral nerve regeneration following crushing or resection injuries in rat sciatic nerves
임해수, 백운이, 구본천,
소속 상세정보
임해수 ( ) - 경희대학교 식품공학과
백운이 ( ) - 경희대학교 식품공학과
구본천 ( ) - 경희대학교 식품공학과
KMID : 0360119950170010096
Abstract
The purpose of this experimental study was to examine and compare the regeneration capacity between crushed nerve & transected nerve.
For this study, 20 Sprague-Dawley female albino rats were used as experimental animals and divided into two groups. In group 1, the sciatic nerves were crushed 6mm. In length for 1 min. using maximum force with a needle holder. In group 2, the
sciatic
nerves were resected 6mm. In length and the gaps were encased by inserting the proximal and distal stumps into each end of silicone tubes.
The animals were sacrificed 1 month & 2 months after the experiment. All specimens were fixed in 2.5% glutaraldehyde and 1% Osmium tetroxide solution then embedded in epon 812 and were cross-sectioned at 1㎛.
After these procedures, specimens were observed under Light microscope.
@ES The results obtained were as follows.
@EN 1. Group 1 showed greter diameters of regenerating nerves than group 2.
2. Group 1 showed greater number of axons than group 2.
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